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KMID : 0614620080510030190
Korean Journal of Gastroenterology
2008 Volume.51 No. 3 p.190 ~ p.193
A Case of Anti-LKM 1 Positive Autoimmune Hepatitis Accompanied by Systemic Lupus Erythematosus
Choi Dae-Han

Kim Hae-Kyung
Park Tae-Il
John Byung-Min
Kang Sung-Hwan
Lee Yoon-Serk
Kim Tae-Hyun
Lee Uh-Joo
Lee Tae-Seung
Yoon Gwi-Ok
Abstract
Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti- LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis. (Korean J Gastroenterol 2008;51:190-193)
KEYWORD
Autoimmune hepatitis, Systemic Lupus erythematosus
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